Following the success of AlexNet in 2012, the field of computer vision dominated progress in AI for approximately six years relative to natural language processing.

Founders Fund was one of the few venture capital firms to invest heavily in Bitcoin starting around 2014-2015, as most VCs were restricted from purchasing cryptocurrencies by their fund's bylaws.

Elad Gil and Founders Fund made a contrarian investment in defense technology company Anduril at a time when it was unpopular for Silicon Valley firms to back weapons companies.