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May 12, 2026

Which markets do VCs feel are the most interesting to invest in today, and which are the hardest to invest in?

14 episodes8 podcastsMar 26, 2025 – Apr 13, 2026
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Venture capital investors are executing a significant capital rotation away from the software sector that dominated the last decade and toward physical assets and infrastructure [3, 9, 12, 18]. This shift is driven by the demands of the AI boom, with investors like Summit Partners focusing on the "physical layer" of technology, including photonics and AI-enabling semiconductors . Other areas of interest include energy and data centers [3, 12]. This reallocation has created a difficult fundraising environment for traditional software companies, which are struggling to raise capital amidst the AI craze . The sector's fall from favor is so pronounced that in the leveraged finance market, software has reportedly gone from a leading category to being **almost unfinanceable** [7, 8]. This broad consensus points to a fundamental change in the venture landscape, where the tangible underpinnings of technology are now valued over the pure-play software models of the previous cycle.

The AI sector itself presents a complex and bifurcated investment landscape, characterized by both intense interest and significant skepticism. On one hand, institutional investors are reported to have "zero interest" in startups not related to AI , with leading VCs adapting their theses to target companies that replace human labor rather than simply sell software [11, 25]. The most interesting technical frontier is seen as models based on pure reinforcement learning . On the other hand, some investors believe the odds of generating a **100x or greater return** on a new AI investment are now extremely low, as the most successful entries were made before the current hype cycle . The frontier model market is particularly challenging due to heavy subsidization from large corporations . A more patient, cyclical view suggests the current AI wave is a bubble, and the most valuable "Gen 2" companies will be founded in the next 2-5 years, following a significant market downturn that rationalizes valuations [1, 4].

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Beyond the dominant AI narrative, investors are identifying contrarian opportunities in overlooked domestic sectors and international markets. The intense focus on AI and SaaS has created a vacuum in consumer internet, presenting a significant opportunity for investors willing to fund businesses in a less competitive landscape [16, 23]. Geographically, China is described as a **"capital starved"** and "least crowded trade," with specific opportunities in robotics . This view of China as an underfunded market exists in tension with the prediction that it will ultimately win the global AI race due to its ingenuity and fewer infrastructure hurdles . Other international markets of interest include India, where the venture exit market is expected to mature over the next decade , and Europe, where the war in Ukraine has made defense technology a newly necessary and acceptable area for venture investment .

Several other sectors are experiencing difficult funding environments, mirroring the challenges in traditional software. In biotech, venture investors are concentrating capital on a smaller number of existing portfolio companies, making it exceptionally difficult for new or struggling firms to raise funds [19, 22, 26]. This has led to a large number of "zombie" biotechs trading for less than their cash on hand . The data streaming market is also cited as a historically difficult category for venture investment, with very few breakout successes . These sector-specific struggles are compounded by a challenging macro environment for LPs, who are navigating a liquidity crunch and the widely expected underperformance of venture fund vintages from 2020 and 2021, which were deployed at peak valuations [2, 5, 30].

What the sources say

Points of agreement

  • There is a major investment shift away from SaaS and enterprise software, which dominated the last decade, and towards physical assets like semiconductors, energy, and data centers.
  • Venture capital fund vintages from 2020-2021 are widely expected to underperform due to high entry valuations and subsequent market compression.
  • AI is the dominant focus for new investment, to the point where non-AI companies are struggling to raise capital from institutional VCs.
  • Capital is becoming more concentrated, with investors focusing on a smaller number of portfolio companies rather than spreading bets widely.

Points of disagreement

  • On AI strategy, some VCs believe the best time for massive returns has passed and are waiting for a 'Gen 2' of companies post-hype, while others see compelling opportunities right now in areas like AI-driven labor replacement.
  • Regarding international markets, some view China as a 'capital starved' contrarian opportunity, while others see it primarily as a formidable competitor that makes certain sectors difficult to invest in.
  • On non-AI opportunities, some investors are targeting the 'physical layer' of technology like semiconductors, while others see a contrarian opportunity in the neglected consumer internet sector.

Sources

Mitchell Green: Why 50% of VCs Should Not Exist (20VC with Harry Stebbings, Mar 7, 2026)

Mitchell Green argues for price discipline, predicts the best AI companies will be founded after a market downturn, and believes China will ultimately win the global AI race.

Ed Grefenstette and Sean Warrington – Venture Market Update (EP.488) (Capital Allocators, Feb 23, 2026)

This episode details the challenging liquidity environment for LPs and highlights contrarian opportunities in 'capital starved' international markets like China.

Josh Wolfe & Brett McGurk – Venture, Geopolitics, and the Next Frontier (EP.476) (Capital Allocators, Dec 8, 2025)

Josh Wolfe identifies a major venture investment shift away from the software that dominated the last decade and towards physical assets like semiconductors and energy.

Legendary Investor Outlines His AI Thesis in 14 Minutes — Bill Gurley (The Tim Ferriss Show, Dec 26, 2025)

Bill Gurley observes that while VCs are almost exclusively funding AI, the window for generating 100x returns on new investments in the sector has likely closed.

Benchmark GP, Victor Lazarte: The 3 Traits All the Best Founders Have (20VC with Harry Stebbings, Apr 14, 2025)

Victor Lazarte explains that the most exciting current venture opportunities are in AI companies that can replace human knowledge workers, a key part of his firm's thesis.

Why This Veteran Venture Capitalist Avoids AI Hype | Jay Hoag Interview (Invest Like the Best, Jun 17, 2025)

Jay Hoag presents a contrarian view, suggesting the intense market focus on AI has created an attractive and less competitive investment opportunity in consumer internet.

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