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May 19, 2026

Which markets outside SF and NYC do VCs feel are the most interesting to invest in today?

22 episodes13 podcastsMar 26, 2025 – May 18, 2026
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Venture capitalists are engaged in a significant debate regarding geographic investment strategy, with a strong contingent arguing for the continued, and even increasing, dominance of Silicon Valley, particularly in artificial intelligence [20, 23]. Marc Andreessen contends that the talent and capital concentration required for cutting-edge AI has led to a re-centralization, asserting that **nearly 100% of high-quality AI companies** are located within a 20-mile radius in the Bay Area [27, 30]. This perspective is supported by Peter Fenton's description of Silicon Valley as a uniquely adaptive "Darwinian ecosystem" most likely to produce future trillion-dollar companies and is reflected in the geographic focus of major initiatives like General Catalyst's AI roll-up strategy, which is almost exclusively centered in San Francisco and New York . This view is underpinned by historical data showing that three states—California, New York, and Massachusetts—have absorbed approximately 75% of all U.S. venture capital over the last decade .

Despite the Bay Area's gravity, some VCs are pursuing opportunities in other domestic markets, driven by strategic specialization and valuation discipline. Los Angeles is identified as a key emerging hub, with investors at M13 predicting it will become the epicenter for the application of AI in the creator economy, culture, and media, even though it was slower to adopt the foundational AI wave [2, 9]. This points to a potential geographic division of labor between core infrastructure development and consumer application layers. Other investors look outside traditional hubs primarily to avoid hyper-competitive deals and inflated valuations; Mitchell Green of Lead Edge Capital, for instance, intentionally limits his firm's portfolio to **less than 10% in the Bay Area**, citing the difficulty of generating returns on investments made at 100x revenue multiples . This strategy acknowledges that world-class companies can be built anywhere, though they may face initial resistance from VCs demanding relocation, as was the case with Duolingo in Pittsburgh .

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Beyond the U.S., VCs identify distinct advantages in international markets. Latin America is highlighted for its capital efficiency, with startups able to reach significant enterprise traction on burn rates as low as **$7,000 per month**, a fraction of their U.S. counterparts . This allows for potentially greater returns on early-stage investments. Japan offers a different model, where corporate venture capital arms from firms like Sony and Japan Airlines provide startups with strategic partnerships, operational expertise, and immediate, large-scale use cases, which can be more valuable than capital alone for de-risking a business model . This aligns with a broader observation that ecosystems with smaller domestic markets, such as Tel Aviv, can succeed by forcing an "international-first" mindset from inception . However, founders in these non-Valley markets must often overcome an implicit local investor bias that presumes lower quality, frequently requiring external validation from a prestigious U.S. entity to secure funding [1, 28].

What the sources say

Points of agreement

  • VCs see strategic advantages in investing outside of core hubs to find capital efficiency or avoid high valuations.
  • International markets present unique opportunities, whether for non-AI sectors, strategic partnerships, or fostering a global-first mindset.
  • A strong belief persists that premier, foundational AI talent and companies are highly concentrated in Silicon Valley.

Points of disagreement

  • One perspective is that Silicon Valley's dominance is increasing due to AI, while another is that tech is decentralizing and opportunities are spreading.
  • Some VCs believe investors outside Silicon Valley are biased against local startups, while others are specifically bullish on emerging local ecosystems like Los Angeles for AI applications.
  • Marc Andreessen claims nearly all quality AI companies are in Silicon Valley, whereas Ruchir Sharma's thesis is to invest in the U.S. broadly for AI and the rest of the world for other sectors.

Sources

SourceryMAR 2, 2026

$1.9B AUM. 200+ Investments. 54 Exits. Inside M13

The M13 venture firm is bullish on Los Angeles's future as a leader in the application of AI for the creator economy and media tech.

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20VC with Harry StebbingsMAR 30, 2026

Marc Andreessen on The Future of VC: Will a16z Go Public & Why Introspection is Dangerous?

Marc Andreessen argues that Silicon Valley's dominance is increasing, driven by the talent and capital concentration required for AI development.

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20VC with Harry StebbingsMAR 26, 2025

Mitchell Green, Founder @ Lead Edge Capital: Why Traditional VC is Broken

Mitchell Green explains his firm's strategy of investing less than 10% of its portfolio in the Bay Area to avoid excessive valuations.

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WTF is FinanceSEP 3, 2025

India vs. China vs. US: Who Wins the Next Decade? | WTF is Finance | Ep 1 ft. Ruchir Sharma

Ruchir Sharma's investment thesis is to invest in the U.S. market exclusively for AI-related opportunities and in the rest of the world for all other sectors.

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The PitchSEP 24, 2025

How Latin American Founders Keep Their Deals Alive

This source highlights the high capital efficiency of startups in Latin America, which can achieve major milestones with very low burn rates.

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20VC with Harry StebbingsFEB 9, 2026

a16z, Anish Acharya: Is SaaS Dead? Do Margins Still Matter? Why We Are Not in an AI Bubble?

This episode notes that ecosystems like Tel Aviv succeed by forcing an international-first mindset due to their small domestic markets.

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